Education

Teaching Interests

CHEM 230, 231 - Organic Chemistry I lecture and lab

CHEM 250 - Survey of Biochemistry

CHEM 330, 331 - Organic Chemistry II lecture and lab

CHEM 415 - Advanced Organic Chemistry

Research

Dr. Chaytor's research group focuses on bioorganic and medicinal chemistry. There are three main areas of research:

1) Synthesis of C-linked carbohydrates

2) Synthesis of cyclic peptides with attractive biological/medicinal properties

3) Synthesis of functionalized cellulose to improve water quality

Scientific Publications

Chaytor, J.L., Al Mughalaq, M., Butler, H. (2017) Development of Online Pre-Laboratory Activities in Organic Chemistry to Improve Students’ Preparation for Laboratory. Journal of Chemical Education, 94 (7): 859-866

Li, J., Chaytor, J.L., Findlay, B., McMullen, L.M., Smith, D.E., Vederas, J.C. (2015) Identification of Didecyldimethylammonium Salts and Salicylic Acid as Antimicrobial Compounds in Commercial Fermented Radish Kimchi. Journal of Agricultural and Food Chemistry, 63, 3053-3058

Towle, K.M., Chaytor, J.L., Liu, H., Austin, P., Roberge, M., Roskelley, C.D., Vederas, J.C. (2013) Synthesis and biological studies of neopetrosiamides as inhibitors of cancer cell invasion. Organic & Biomolecular Chemistry, 11: 1476-1481

Chaytor, J.L., Tokarew, J.M., Wu, L.K., Leclere, M., Tam, R.Y., Capicciotti, C.J., Guolla, L., von Moos, E., Findlay, C.S., Allan, D.S., Ben, R.N. (2012) Inhibiting Ice Recrystallization and Optimization of Cell Viability after Cryopreservation. Glycobiology. 22: 122-133

Barriuso, J., Nguyen, D.T., Li., J.W.-H., Roberts, J.N., MacNevin, G., Chaytor, J.L., Marcus, S.L., Vederas, J.C., Ro, D.-K. (2011) Double Oxidation of the Cyclic Nonaketide Dihydromonacolin L to Monacolin J by a Single Cytochrome P450 Monooxygenase, LovA. Journal of the American Chemical Society. 133: 8078-8081

Wu, L.K., Tokarew, J.M., Chaytor, J.L., Guolla, L., von Moos, E., Li, Y., Palii, C., Ben, R.N., Allan, D.S. (2010) Carbohydrate-mediated inhibition of ice recrystallization in cryopreserved human umbilical cord blood. Carbohydrate Research. 346: 86-93

Chaytor, J.L., Ben, R.N. (2010) Assessing the Ability of a Short Fluorinated Antifreeze Glycopeptide and a Fluorinated Carbohydrate Derivative to Inhibit Ice Recrystallization. Bioorganic and Medicinal Chemistry Letters. 20: 5251-5254

Tam, R.Y., Ferreira, S.S., Czechura, P., Chaytor, J.L., Ben, R.N. (2008) Hydration Index: A Better Parameter for Explaining Small Molecule Hydration in Inhibition of Ice Recrystallization. Journal of the American Chemical Society. 130: 17494-17501

Metallinos, C., Dudding, T., Zaifman, J., Chaytor, J.L., Taylor, N.J. (2007) An Experimental and Theoretical Study of the Asymmetric Lithiation of 1,2,3,5,6,7-Hexahydro-3a,4a-diazacyclopenta[def]phenanthren-4-one. Journal of Organic Chemistry. 72: 957-963

Metallinos, C.; Barrett, F.B.; Chaytor, J.L.; Heska, M.E.A. (2004) A Benzimidazole-Based N-Heterocyclic Carbene Derived from 1,10-Phenanthroline. Organic Letters. 6: 3641-3644

Patents

Ben, R.N., Tam, R.Y., Ferreira, S.S., Czechura, P., Chaytor, J.L. “C-linked AFGP Analogues”, filing date: July 31, 2008, U.S. Provisional Patent Application Serial No. 61 / 085,058

Honors and Awards

2020 - Franc A. Landee Teaching Excellence Award

2019 - 1st State Bank RUBY (Recognizing the Upward, Bright, and Young) Award 

2017 - SVSU Undergraduate Research Program Faculty Mentor Award